Intense sonication of liquids generates sound waves that propagate into the liquid media resulting in alternating high-pressure and low-pressure cycles. During the low-pressure cycle, high-intensity small vacuum bubbles are created in the liquid.

The main emphasis of the company's activities is the conception, development and production of ultrasonic devices for the use in laboratory and industrial applications. Ultrasonic devices made by Hielscher are used for lab samples, pilot scale processing or full scale production. This includes ultrasonic devices for the ultrasonication of any liquid volume, from several microliters through hundreds of cubicmeters per hour.